Smooth Muscle Cell–targeted RNA Aptamer Inhibits Neointimal Formation

Inhibition of vascular smooth muscle cell (VSMC) proliferation by drug eluting stents has markedly reduced intimal hyperplasia and subsequent in-stent restenosis. However, the effects of antiproliferative drugs on endothelial cells (EC) contribute to delayed re-endothelialization and late stent thro...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Thiel, William H, Esposito, Carla L, Dickey, David D, Dassie, Justin P, Long, Matthew E, Adam, Joshua, Streeter, Jennifer, Schickling, Brandon, Takapoo, Maysam, Flenker, Katie S, Klesney-Tait, Julia, Franciscis, Vittorio de, Miller, Francis J, Giangrande, Paloma H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886937/
https://ncbi.nlm.nih.gov/pubmed/26732878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.235
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