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Transcriptional Profiling of Rapamycin-Treated Fibroblasts From Hypertrophic and Keloid Scars

Excess scar formation after cutaneous injury can result in hypertrophic scar (HTS) or keloid formation. Modern strategies to treat pathologic scarring represent nontargeted approaches that produce suboptimal results. Mammalian target of rapamycin (mTOR), a central mediator of inflammation, has been...

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Dettagli Bibliografici
Pubblicato in:Ann Plast Surg
Autori principali: Wong, Victor W., You, Fanglei, Januszyk, Michael, Gurtner, Geoffrey C., Kuang, Anna A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886898/
https://ncbi.nlm.nih.gov/pubmed/24835866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SAP.0b013e31826956f6
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