Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes

Neuronal activity causes the rapid expression of immediate early genes that are crucial for experience-driven changes to synapses, learning, and memory. Here, using both molecular and genome-wide next-generation sequencing methods, we report that neuronal activity stimulation triggers the formation...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Madabhushi, Ram, Gao, Fan, Pfenning, Andreas R., Pan, Ling, Yamakawa, Satoko, Seo, Jinsoo, Rueda, Richard, Phan, Trongha, Yamakawa, Hidekuni, Pao, Ping-Chieh, Stott, Ryan T., Gjoneska, Elizabeta, Nott, Alexi, Cho, Sukhee, Kellis, Manolis, Tsai, Li-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886855/
https://ncbi.nlm.nih.gov/pubmed/26052046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.032
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