Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression

Inflammation may be maladaptive to the control of viral infection when it impairs interferon (IFN) responses, enhancing viral replication and spread. Dysregulated immunity as a result of inappropriate innate inflammatory responses is a hallmark of chronic viral infections such as, hepatitis B virus...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: MacParland, Sonya A., Ma, Xue-Zhong, Chen, Limin, Khattar, Ramzi, Cherepanov, Vera, Selzner, Markus, Feld, Jordan J., Selzner, Nazia, McGilvray, Ian D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886784/
https://ncbi.nlm.nih.gov/pubmed/27009955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02557-15
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