B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts

Dengue virus (DENV) infection results in the production of both type-specific and cross-neutralizing antibodies. While immunity to the infecting serotype is long-lived, heterotypic immunity wanes a few months after infection. Epidemiological studies link secondary heterotypic infections with more se...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Priyamvada, Lalita, Cho, Alice, Onlamoon, Nattawat, Zheng, Nai-Ying, Huang, Min, Kovalenkov, Yevgeniy, Chokephaibulkit, Kulkanya, Angkasekwinai, Nasikarn, Pattanapanyasat, Kovit, Ahmed, Rafi, Wilson, Patrick C., Wrammert, Jens
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Cellular Response to Infection
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886779/
https://ncbi.nlm.nih.gov/pubmed/27030262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03203-15
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