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The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis

Although autophagy controls cell death and survival, underlying mechanisms are poorly understood and it is unknown if autophagy just affects whether or not cells die or also controls other aspects of programmed cell death. MAP3K7 is a tumor suppressor gene associated with poor disease-free survival...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Goodall, Megan L., Fitzwalter, Brent, Zahedi, Shadi, Wu, Min, Rodriguez, Diego, Mulcahy-Levy, Jean M., Green, Douglas R., Morgan, Michael, Cramer, Scott D., Thorburn, Andrew
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886731/
https://ncbi.nlm.nih.gov/pubmed/27219062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.04.018
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