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Interferon-γ facilitates hepatic antiviral T cell retention for the maintenance of liver-induced systemic tolerance

Persistent exposure to liver pathogens leads to systemic antigen-specific tolerance, a major cause of chronicity during hepatotropic infection. The mechanism regarding how this systemic tolerance is maintained remains poorly elucidated. In a well established mouse model of hepatitis B virus (HBV) pe...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Zeng, Zhutian, Li, Lu, Chen, Yongyan, Wei, Haiming, Sun, Rui, Tian, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886358/
https://ncbi.nlm.nih.gov/pubmed/27139489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151218
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