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The Mycobacterium bovis BCG prime-Rv0577 DNA boost vaccination induces a durable Th1 immune response in mice

Tuberculosis remains a major global health problem and effective vaccines are urgently needed. In this study, we used the combined DNA- and protein-based vaccines of immunodominant antigen Rv0577 to boost BCG and evaluated their immunogenicity in BALB/c mice. Our data suggest that the booster vaccin...

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Bibliografiske detaljer
Udgivet i:Acta Biochim Biophys Sin (Shanghai)
Main Authors: Gu, Dongqing, Chen, Wei, Mi, Youjun, Gong, Xueli, Luo, Tao, Bao, Lang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886249/
https://ncbi.nlm.nih.gov/pubmed/26922320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmw010
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