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Atorvastatin blocks increased l-type Ca(2+) current and cell injury elicited by angiotensin II via inhibiting oxide stress

The l-type Ca(2+) current (I(Ca,l)) plays a crucial role in shaping action potential and is involved in cardiac arrhythmia. Statins have been demonstrated to contribute to anti-apoptotic and anti-arrhythmic effects in the heart. Here, we examined whether atorvastatin regulates the I(Ca,l) and cell i...

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Bibliografski detalji
Izdano u:Acta Biochim Biophys Sin (Shanghai)
Glavni autori: Ma, Yanzhuo, Kong, Lingfeng, Qi, Shuying, Wang, Dongmei
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886248/
https://ncbi.nlm.nih.gov/pubmed/26940997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmw009
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