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Effects of the N terminus of mouse DNA polymerase κ on the bypass of a guanine-benzo[a]pyrenyl adduct

DNA polymerase κ (Polκ), one of the typical member of the Y-family DNA polymerases, has been demonstrated to bypass the 10S (+)-trans-anti-benzo[a]pyrene diol epoxide-N(2)-deoxyguanine adducts (BPDE-dG) efficiently and accurately. A large structural gap between the core and little finger as well as...

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Bibliografiske detaljer
Udgivet i:J Biochem
Main Authors: Liu, Yang, Ma, Xiaolu, Guo, Caixia
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885933/
https://ncbi.nlm.nih.gov/pubmed/26634445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv118
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