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Melanocortin 1 Receptor: Structure, Function, and Regulation

The melanocortin 1 receptor (MC1R) is a melanocytic G(s) protein coupled receptor that regulates skin pigmentation, UV responses, and melanoma risk. It is a highly polymorphic gene, and loss of function correlates with a fair, UV-sensitive, and melanoma-prone phenotype due to defective epidermal mel...

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Publicat a:Front Genet
Autors principals: Wolf Horrell, Erin M., Boulanger, Mary C., D’Orazio, John A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885833/
https://ncbi.nlm.nih.gov/pubmed/27303435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00095
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