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Validation and Application of a Simple UHPLC–MS-MS Method for the Enantiospecific Determination of Warfarin in Human Urine

A simple and rapid liquid chromatographic–tandem mass spectrometric method has been developed and validated for the enantiospecific determination of R- and S-warfarin in human urine. Warfarin enantiomers were extracted from urine using methyl tert-butyl ether. Chromatographic separation of warfarin...

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Detalhes bibliográficos
Publicado no:J Chromatogr Sci
Main Authors: Alshogran, Osama Y., Ocque, Andrew J., Leblond, François A., Pichette, Vincent, Nolin, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885390/
https://ncbi.nlm.nih.gov/pubmed/26657732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chromsci/bmv186
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