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MicroRNA-195a-5p inhibits mouse medullary thymic epithelial cells proliferation by directly targeting Smad7

MiR-195 has been implicated in inhibiting cell proliferation in different types of tumors. Whether it contributes to the process of thymic epithelial cells (TECs) proliferation remains unclear. In this study, we found that miR-195a-5p was highly up-regulated in the TECs isolated from the aging mice....

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Publicado en:Acta Biochim Biophys Sin (Shanghai)
Autores principales: Guo, Dongguang, Ye, Yaqiong, Qi, Junjie, Xu, Lifeng, Zhang, Lihua, Tan, Xiaotong, Tan, Zhigang, Yu, Xiaofang, Zhang, Yuan, Ma, Yongjiang, Li, Yugu
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885129/
https://ncbi.nlm.nih.gov/pubmed/26837421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmv136
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