Re-Designed Recombinant Hepatitis B Virus Vectors Enable Efficient Delivery of Versatile Cargo Genes to Hepatocytes with Improved Safety

Hepatitis B virus (HBV) takes humans as its sole natural host, and productive infection in vivo is restricted exclusively to hepatocytes in the liver. Consequently, HBV-derived viral vectors are attractive candidates for liver-targeting gene therapies. Previously, we developed a novel recombinant HB...

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Publicado no:Viruses
Main Authors: Bai, Weiya, Cui, Xiaoxian, Chen, Ruidong, Tao, Shuai, Hong, Ran, Zhang, Jiming, Zhang, Junqi, Wang, Yongxiang, Xie, Youhua, Liu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885084/
https://ncbi.nlm.nih.gov/pubmed/27171107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8050129
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