Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia

Palliative care in acute myeloid leukaemia (AML) is inadequate. For elderly patients, unfit for intensive chemotherapy, median survival is 2–3 months. As such, there is urgent demand for low-toxic palliative alternatives. We have repositioned two commonly administered anti-leukaemia drugs, valproic...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Leitch, Calum, Osdal, Tereza, Andresen, Vibeke, Molland, Maren, Kristiansen, Silje, Nguyen, Xuan Nhi, Bruserud, Øystein, Gjertsen, Bjørn Tore, McCormack, Emmet
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884979/
https://ncbi.nlm.nih.gov/pubmed/26812881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6991
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