CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR-425

Hepatocellular carcinoma (HCC) is a common and leading cause of death worldwide. Here, we identified that a cell-cell adhesion gene, CTNNA3, is a tumor suppressor in HCC. CTNNA3 inhibited the proliferation, migration and invasion of HCC cell lines. In these cells, CTNNA3 inhibited Akt signal, and in...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: He, Bing, Li, Ting, Guan, Lei, Liu, Fang-E, Chen, Xue-Mei, Zhao, Jing, Lin, Song, Liu, Zhi-Zhen, Zhang, Hu-Qin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884977/
https://ncbi.nlm.nih.gov/pubmed/26882563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6978
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