Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis

Abnormal overexpression of CXCL13 is observed in many inflamed tissues and in particular in autoimmune diseases. Myasthenia gravis (MG) is a neuromuscular disease mainly mediated by anti-acetylcholine receptor autoantibodies. Thymic hyperplasia characterized by ectopic germinal centers (GCs) is a co...

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Vydáno v:Oncotarget
Hlavní autoři: Weiss, Julia Miriam, Robinet, Marieke, Aricha, Revital, Cufi, Perrine, Villeret, Bérengère, Lantner, Frida, Shachar, Idit, Fuchs, Sara, Souroujon, Miriam C., Berrih-Aknin, Sonia, Le Panse, Rozen
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper: Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884937/
https://ncbi.nlm.nih.gov/pubmed/26771137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6885
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