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Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells

The clinical promise of cancer immunotherapy relies on the premise that the immune system can recognize and eliminate tumor cells identified as non-self. However, tumors can evade host immune surveillance through multiple mechanisms, including epigenetic silencing of genes involved in antigen proces...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gameiro, Sofia R., Malamas, Anthony S., Tsang, Kwong Y., Ferrone, Soldano, Hodge, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884926/
https://ncbi.nlm.nih.gov/pubmed/26862729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7180
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