Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation

BACKGROUND: APOBEC3B is a cytosine deaminase implicated in immune response to viral infection, cancer predisposition and carcinogenesis. Germline APOBEC3B deletion is more common in East Asian women and confers a modest risk to breast cancer in both East Asian and Caucasian women. Analysis of tumour...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Wen, Wei Xiong, Soo, Jaslyn Sian-Siu, Kwan, Pui Yoke, Hong, Elaine, Khang, Tsung Fei, Mariapun, Shivaani, Lee, Christine Shu-Mei, Hasan, Siti Norhidayu, Rajadurai, Pathmanathan, Yip, Cheng Har, Mohd Taib, Nur Aishah, Teo, Soo Hwang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884363/
https://ncbi.nlm.nih.gov/pubmed/27233495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0717-1
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