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The negatively charged carboxy-terminal tail of β-tubulin promotes proper chromosome segregation

Despite the broadly conserved role of microtubules in chromosome segregation, we have a limited understanding of how molecular features of tubulin proteins contribute to the underlying mechanisms. Here we investigate the negatively charged carboxy-terminal tail domains (CTTs) of α- and β-tubulins, u...

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Publicat a:Mol Biol Cell
Autors principals: Fees, Colby P., Aiken, Jayne, O’Toole, Eileen T., Giddings, Thomas H., Moore, Jeffrey K.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884069/
https://ncbi.nlm.nih.gov/pubmed/27053662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-05-0300
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