Inhibitory effects of H-Ras/Raf-1-binding affibody molecules on synovial cell function

Affibody molecules specific for H-Ras and Raf-1 were evaluated for their ability to inhibit synovial cell function. Affibody molecules targeting H-Ras (Z(ras122), Z(ras220), and Z(ras521)) or Raf-1 (Z(raf322)) were introduced into the MH7A synovial cell line using two delivery methods: transfection...

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Bibliographic Details
Published in:AMB Express
Main Authors: Shibasaki, Seiji, Karasaki, Miki, Gräslund, Torbjörn, Nygren, Per-Åke, Sano, Hajime, Iwasaki, Tsuyoshi
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884024/
https://ncbi.nlm.nih.gov/pubmed/26267111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-014-0082-3
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