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Targeting met mediated epithelial-mesenchymal transition in the treatment of breast cancer

Mesenchymal epithelial transition factor receptor (Met) is a receptor tyrosine kinase that plays a critical role in promoting cancer cell malignant progression. Met is activated by its ligand hepatocyte growth factor (HGF). HGF-dependent Met activation plays an important role in stimulating epitheli...

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Bibliografiske detaljer
Udgivet i:Clin Transl Med
Hovedforfatter: Sylvester, Paul W
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883993/
https://ncbi.nlm.nih.gov/pubmed/26932375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-014-0030-5
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