Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc

Human GLP-1 (glucagon-like peptide-1) can produce a remarkable improvement in glycemic control in patients with type 2 diabetes. However, its clinical benefits are limited by its short half-life, which is less than 2 min because of its small size and rapid enzymatic inactivation by dipeptidyl peptid...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Yang, Yi, Chen, Fang, Wan, Deyou, Liu, Yunhui, Yang, Li, Feng, Hongru, Cui, Xinling, Gao, Xin, Song, Haifeng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883776/
https://ncbi.nlm.nih.gov/pubmed/27232339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156449
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