Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila

Altered expression of the E3 ubiquitin ligase UBE3A, which is involved in protein degradation through the proteasome-mediated pathway, is associated with neurodevelopmental and behavioral defects observed in Angelman syndrome (AS) and autism. However, little is known about the neuronal function of U...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Li, Wenhua, Yao, Aiyu, Zhi, Hui, Kaur, Kuldeep, Zhu, Yong-chuan, Jia, Mingyue, Zhao, Hui, Wang, Qifu, Jin, Shan, Zhao, Guoli, Xiong, Zhi-Qi, Zhang, Yong Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883773/
https://ncbi.nlm.nih.gov/pubmed/27232889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006062
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