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Blockade of CD354 (TREM-1) Ameliorates Anti-GBM-Induced Nephritis

CD354, Triggering Receptor of Myeloid Cells-1 (TREM-1), is a potent amplifier of myeloid immune responses. Our goal was to determine the expression and function of TREM-1 in immune-mediated nephritis. An anti-glomerular basement membrane antibody (anti-GBM)-induced nephritis model was employed, wher...

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Bibliographic Details
Published in:Inflammation
Main Authors: Du, Yong, Wu, Tianfu, Zhou, Xin J., Davis, Laurie S., Mohan, Chandra
Format: Artigo
Language:Inglês
Published: Springer US 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883274/
https://ncbi.nlm.nih.gov/pubmed/27083877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-016-0351-1
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