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Rituximab for Rheumatoid Arthritis

Rituximab is a chimeric monoclonal antibody directed at the CD20 molecule on the surfaces of some but not all B cells. It depletes almost all peripheral B cells, but other niches of B cells are variably depleted, including synovium. Its mechanism of action in rheumatoid arthritis (RA) is only partia...

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Detalles Bibliográficos
Publicado en:Rheumatol Ther
Main Authors: Cohen, Marc D., Keystone, Edward
Formato: Artigo
Idioma:Inglês
Publicado: Springer Healthcare 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883263/
https://ncbi.nlm.nih.gov/pubmed/27747531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40744-015-0016-9
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