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Mannitol Preserves the Viscoelastic Properties of Hyaluronic Acid in an In Vitro Model of Oxidative Stress

INTRODUCTION: Viscosupplementation by intra-articular injection of hyaluronic acid (HA) is a widely used treatment for lower limb osteoarthritis. However, the injected HA is rapidly degraded by reactive oxygen species (ROS), limiting its time of intra-articular residence. Optimizing clinical effecti...

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Bibliografiske detaljer
Udgivet i:Rheumatol Ther
Main Authors: Conrozier, Thierry, Mathieu, Pierre, Rinaudo, Marguerite
Format: Artigo
Sprog:Inglês
Udgivet: Springer Healthcare 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883257/
https://ncbi.nlm.nih.gov/pubmed/27747759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40744-014-0001-8
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