Ventilatory long-term facilitation is evident after initial and repeated exposure to intermittent hypoxia in mice genetically depleted of brain serotonin

Our study was designed to determine if central nervous system (CNS) serotonin is required for the induction of ventilatory long-term facilitation (LTF) in intact, spontaneously breathing mice. Nineteen tryptophan hydroxylase 2-deficient (Tph2(−/−)) mice, devoid of serotonin in the CNS, and their wil...

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Bibliographic Details
Published in:J Appl Physiol (1985)
Main Authors: Hickner, Stephen, Hussain, Najaah, Angoa-Perez, Mariana, Francescutti, Dina M., Kuhn, Donald M., Mateika, Jason H.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882922/
https://ncbi.nlm.nih.gov/pubmed/24336886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01197.2013
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