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The N-terminal 22 amino acid residues in the lactose permease of Escherichia coli are not obligatory for membrane insertion or transport activity.

When the lactose (lac) permease of Escherichia coli is expressed from the lac promoter at relatively low rates, deletion of amino acid residues 2-8 (delta 7) or 2-9 (delta 8) from the hydrophilic N terminus has a relatively minor effect on the ability of the permease to catalyze active lactose trans...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Bibi, E, Stearns, S M, Kaback, H R
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1565610/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3180
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