Control of Trx1 redox state modulates protection against methyl methanesulfonate-induced DNA damage via stabilization of p21

Thioredoxin 1 (Trx1) is known to play an important role in protecting against cell death. However, the mechanism for control of Trx1 in cell death resulting from DNA damage has not been fully investigated. In this study, we used the DNA-damaging agent methyl methanesulfonate (MMS) to investigate the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biochem
Egile Nagusiak: Gu, Li, Gao, Wei, Yang, Hui Min, Wang, Bei Bei, Wang, Xiao Na, Xu, Jianguo, Zhang, Hong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Regular Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882645/
https://ncbi.nlm.nih.gov/pubmed/26276860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv080
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