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Autocrine inhibition of the c-fms proto-oncogene reduces breast cancer bone metastasis assessed with in vivo dual-modality imaging

Breast cancer cells preferentially home to the bone microenvironment, which provides a unique niche with a network of multiple bidirectional communications between host and tumor, promoting survival and growth of bone metastases. In the bone microenvironment, the c-fms proto-oncogene that encodes fo...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Jeffery, Justin J, Lux, Katie, Vogel, John S, Herrera, Wynetta D, Greco, Stephen, Woo, Ho-Hyung, AbuShahin, Nisreen, Pagel, Mark D, Chambers, Setsuko K
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882610/
https://ncbi.nlm.nih.gov/pubmed/24599884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214522588
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