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An RNA-aptamer-based two-color CRISPR labeling system

The spatial organization and dynamics of chromatin play important roles in essential biological functions. However, direct visualization of endogenous genomic loci in living cells has proven to be laborious until the recent development of CRISPR-Cas9-based chromatin labeling methods. These methods r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Siyuan, Su, Jun-Han, Zhang, Feng, Zhuang, Xiaowei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882555/
https://ncbi.nlm.nih.gov/pubmed/27229896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26857
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