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Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition

Butyrate has been used to treat different inflammatory disease with positive outcomes, the mechanisms by which butyrate exerts its anti-inflammatory effects remain largely undefined. Here we proposed a new mechanism that butyrate manipulate endogenous host defense peptides (HDPs) which contributes t...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Xiong, Haitao, Guo, Bingxiu, Gan, Zhenshun, Song, Deguang, Lu, Zeqing, Yi, Hongbo, Wu, Yueming, Wang, Yizhen, Du, Huahua
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882515/
https://ncbi.nlm.nih.gov/pubmed/27230284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27070
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