Structural Divergence of the Group I Intron Binding Surface in Fungal Mitochondrial Tyrosyl-tRNA Synthetases That Function in RNA Splicing

The mitochondrial tyrosyl-tRNA synthetases (mtTyrRSs) of Pezizomycotina fungi, a subphylum that includes many pathogenic species, are bifunctional proteins that both charge mitochondrial tRNA(Tyr) and act as splicing cofactors for autocatalytic group I introns. Previous studies showed that one of th...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Lamech, Lilian T., Saoji, Maithili, Paukstelis, Paul J., Lambowitz, Alan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2016
Ämnen:
Protein Structure and Folding
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882457/
https://ncbi.nlm.nih.gov/pubmed/27036943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.725390
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