The combination of HLA-B*15:01 and DRB1*15:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in patients with advanced pancreatic cancer

PURPOSE: In a phase III study of gemcitabine plus erlotinib for advanced pancreatic cancer conducted in Canada, the incidence of interstitial lung disease (ILD) was 3.5 %. However, the incidence of ILD was reported as high as 8.5 % in a Japanese phase II study. These results suggest the influence of...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Nishimura, Meiko, Toyoda, Masanori, Takenaka, Kei, Imamura, Yoshinori, Chayahara, Naoko, Kiyota, Naomi, Mukohara, Toru, Kotake, Takeshi, Tsuji, Akihito, Saito, Kosuke, Saito, Yoshiro, Minami, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882349/
https://ncbi.nlm.nih.gov/pubmed/27100735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3026-6
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