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Linagliptin Attenuates Diabetes-Induced Cerebral Pathological Neovascularization in a Blood Glucose-Independent Manner: Potential Role of ET-1

AIMS: We have shown that glycemic control with metformin or endothelin-1 (ET-1) inhibition with bosentan prevents and restores diabetes-mediated cerebral pathological remodeling and neovascularization. Our recent data suggest that linagliptin, a member of the dipeptidyl peptidase-4 inhibitor class o...

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Publicat a:Life Sci
Autors principals: Abdelsaid, Mohammed, Williams, Raeonda, Hardigan, Trevor, Ergul, Adviye
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882278/
https://ncbi.nlm.nih.gov/pubmed/26631506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2015.11.026
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