Contribution of Estrone Sulfate to Cell Proliferation in Aromatase Inhibitor (AI) -Resistant, Hormone Receptor-Positive Breast Cancer

Aromatase inhibitors (AIs) effectively treat hormone receptor-positive postmenopausal breast cancer, but some patients do not respond to treatment or experience recurrence. Mechanisms of AI resistance include ligand-independent activation of the estrogen receptor (ER) and signaling via other growth...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Higuchi, Toru, Endo, Megumi, Hanamura, Toru, Gohno, Tatsuyuki, Niwa, Toshifumi, Yamaguchi, Yuri, Horiguchi, Jun, Hayashi, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882040/
https://ncbi.nlm.nih.gov/pubmed/27228187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155844
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