Predicting Ancestral Segmentation Phenotypes from Drosophila to Anopheles Using In Silico Evolution

Molecular evolution is an established technique for inferring gene homology but regulatory DNA turns over so rapidly that inference of ancestral networks is often impossible. In silico evolution is used to compute the most parsimonious path in regulatory space for anterior-posterior patterning linki...

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Udgivet i:PLoS Genet
Main Authors: Rothschild, Jeremy B., Tsimiklis, Panagiotis, Siggia, Eric D., François, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882032/
https://ncbi.nlm.nih.gov/pubmed/27227405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006052
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