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MicroRNA-1301-Mediated RanGAP1 Downregulation Induces BCR-ABL Nuclear Entrapment to Enhance Imatinib Efficacy in Chronic Myeloid Leukemia Cells

Chronic myeloid leukemia (CML) is a myeloproliferative disease. Imatinib (IM), the first line treatment for CML, is excessively expensive and induces various side effects in CML patients. Therefore, it is essential to investigate a new strategy for improving CML therapy. Our immunoblot data revealed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lin, Tsung-Yao, Chen, Ku-Chung, Liu, Hsing-Jin Eugene, Liu, Ann-Jeng, Wang, Kun-Li, Shih, Chwen-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881950/
https://ncbi.nlm.nih.gov/pubmed/27228340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156260
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