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Squamous Metaplasia Is Increased in the Bronchial Epithelium of Smokers with Chronic Obstructive Pulmonary Disease

AIMS: To quantify the extent of squamous metaplasia in bronchial biopsies and relate it to the presence of chronic obstructive pulmonary disease (COPD), a smoking-related pathology. METHODS: Bronchial biopsies (n = 15 in each group) from smokers with COPD GOLD stage1 and GOLD stage2, smokers without...

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Veröffentlicht in:PLoS One
Hauptverfasser: Rigden, Helen M., Alias, Ahmad, Havelock, Thomas, O'Donnell, Rory, Djukanovic, Ratko, Davies, Donna E., Wilson, Susan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881906/
https://ncbi.nlm.nih.gov/pubmed/27228128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156009
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