Data Interoperability of Whole Exome Sequencing (WES) Based Mutational Burden Estimates from Different Laboratories

Immune checkpoint inhibitors, which unleash a patient’s own T cells to kill tumors, are revolutionizing cancer treatment. Several independent studies suggest that higher non-synonymous mutational burden assessed by whole exome sequencing (WES) in tumors is associated with improved objective response...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Qiu, Ping, Pang, Ling, Arreaza, Gladys, Maguire, Maureen, Chang, Ken C. N., Marton, Matthew J., Levitan, Diane
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
Témata:
Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881477/
https://ncbi.nlm.nih.gov/pubmed/27136543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050651
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