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Protective Effect of Tyrosol and S-Adenosylmethionine against Ethanol-Induced Oxidative Stress of Hepg2 Cells Involves Sirtuin 1, P53 and Erk1/2 Signaling

Oxidative stress plays a major role in ethanol-induced liver damage, and agents with antioxidant properties are promising as therapeutic opportunities in alcoholic liver disease. In the present work, we investigated the effect of S-adenosylmethionine (AdoMet), Tyrosol (Tyr), and their combination on...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Stiuso, Paola, Bagarolo, Maria Libera, Ilisso, Concetta Paola, Vanacore, Daniela, Martino, Elisa, Caraglia, Michele, Porcelli, Marina, Cacciapuoti, Giovanna
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881448/
https://ncbi.nlm.nih.gov/pubmed/27128904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050622
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