Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand Alone Graft

Clinical application of umbilical cord blood (UCB) as a source of hematopoietic stem cells for transplantation is limited by low CD34+ cell dose, increased risk of graft failure and slow hematopoietic recovery. While the cell dose limitation is partially mitigated by using two UCB units, larger dose...

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Udgivet i:Cell Stem Cell
Main Authors: Wagner, John E., Brunstein, Claudio G., Boitano, Anthony E., DeFor, Todd E., McKenna, David, Sumstad, Darin, Blazar, Bruce R., Tolar, Jakub, Le, Chap, Jones, Julie, Cooke, Michael P., Bleul, Conrad C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881386/
https://ncbi.nlm.nih.gov/pubmed/26669897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.10.004
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