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Analgesic effect and possible mechanism of SCH772984 intrathecal injection on rats with bone cancer pain()
This study is to establish a model of rat tibial osteocarcinoma pain, intrathecally inject specific ERK1/2 inhibitors SCH772984, observe the analgesic effect, and discuss the influence of ERK-P90RSK-Fos signal path in bone cancer pain. Forty female SD rats were randomly divided into 5 groups. Establ...
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Publicado no: | Saudi Pharm J |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881153/ https://ncbi.nlm.nih.gov/pubmed/27275127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2016.04.017 |
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