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Potential role of oxidative stress-induced apoptosis in mediating chromosomal rearrangements in nasopharyngeal carcinoma

BACKGROUND: Genetic aberrations have been identified in nasopharyngeal carcinoma (NPC), however, the underlying mechanism remains elusive. There are increasing evidences that the apoptotic nuclease caspase-activated deoxyribonuclease (CAD) is one of the players leading to translocation in leukemia....

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Tan, Sang-Nee, Sim, Sai-Peng, Khoo, Alan S. B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880972/
https://ncbi.nlm.nih.gov/pubmed/27231526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-016-0103-9
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