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Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1

The constitutively-expressed cyclooxygenase 1 (COX-1) and the inducible COX-2 are both involved in the conversion of arachidonic acid (AA) to prostaglandins (PGs). However, the functional roles of COX-1 at the cellular level remain unclear. We hypothesized that by comparing differential gene express...

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Detalhes bibliográficos
Publicado no:Genomics Proteomics Bioinformatics
Main Authors: Islam, Abul B.M.M.K., Dave, Mandar, Amin, Sonia, Jensen, Roderick V., Amin, Ashok R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880957/
https://ncbi.nlm.nih.gov/pubmed/27012456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gpb.2014.09.005
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