Transactivation and transformation by Myb are negatively regulated by a leucine-zipper structure.

The negative regulatory domain of the c-myb protooncogene product (c-Myb) normally represses transcriptional activation by c-Myb. We show here that a leucine-zipper structure is a component of the negative regulatory domain, because its disruption markedly increases both the transactivating and tran...

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Hauptverfasser: Kanei-Ishii, C, MacMillan, E M, Nomura, T, Sarai, A, Ramsay, R G, Aimoto, S, Ishii, S, Gonda, T J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC48809/
https://ncbi.nlm.nih.gov/pubmed/1557416
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