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Primary sex determination of placental mammals: a modelling study uncovers dynamical developmental constraints in the formation of Sertoli and granulosa cells

BACKGROUND: Primary sex determination in placental mammals is a very well studied developmental process. Here, we aim to investigate the currently established scenario and to assess its adequacy to fully recover the observed phenotypes, in the wild type and perturbed situations. Computational modell...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Sánchez, Lucas, Chaouiya, Claudine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880855/
https://ncbi.nlm.nih.gov/pubmed/27229461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0282-3
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