Carbonic anhydrase IX is a marker of hypoxia and correlates with higher Gleason scores and ISUP grading in prostate cancer

BACKGROUND: Carbonic anhydrase IX is a member of α-carbonic anhydrases that is preferentially expressed in solid tumors. It enables bicarbonate transport across the plasma membrane, neutralizing intracellular pH and conferring to cancer cells a survival advantage in hypoxic/acidic microenvironments....

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Foilsithe in:Diagn Pathol
Main Authors: Ambrosio, Maria Raffaella, Di Serio, Claudia, Danza, Giovanna, Rocca, Bruno Jim, Ginori, Alessandro, Prudovsky, Igor, Marchionni, Niccolò, del Vecchio, Maria Teresa, Tarantini, Francesca
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2016
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880832/
https://ncbi.nlm.nih.gov/pubmed/27225200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-016-0495-1
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