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Dihydro pyrimidine dehydrogenase deficiency in patients treated with capecitabine based regimens: a tertiary care centre experience
BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) enzyme is the rate limiting step in the metabolism of capecitabine, and its deficiency leads to severe toxicities and rarely, death. METHODS: A total of 506 patients were treated in the GI Medical Oncology unit of our institution with capecitabine co...
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| Publicado no: | J Gastrointest Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AME Publishing Company
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4880770/ https://ncbi.nlm.nih.gov/pubmed/27284470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2016.03.02 |
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